MomTreatment Dashboard

Lana Markey · Study 2023-0621 · Dr. Andreeff, MD Anderson
Latest labs: 2026-05-12 · Built 2026-05-12 19:28:21
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TODAY · TUESDAY
May 12, 2026
Cycle 1
Day 23 of 35 · Watch week
66% through Cycle 1 · 18% through the first 4 cycles (trial can run up to 2 years)
Medicine schedule
💉NadunolimabNext in 13 days (May 25)
💉AzacitidineWeek starts in 13 days (May 25)

What Mom's Labs Say Today

Auto-generated from Mom's MyChart labs with AI assistance (Claude Sonnet). This is an informational summary, not medical advice or a clinical assessment — any questions or concerns should go to her care team at MD Anderson. Every numeric claim is verified against the source data.

Today is Day 23 of Cycle 1 — Lana is deep in the bone marrow recovery window, the stretch after induction chemotherapy does its hardest work and the marrow begins, slowly, to find its footing again. Her Hgb (hemoglobin) came in at 9.1 today, a welcome bounce from yesterday's 7.9 — almost certainly reflecting the red cell transfusion she received on May 11 (more on that below). Her ANC (neutrophils), the infection-fighting white cells, sits at 0.2 — severely neutropenic, and has been hovering in that range all week. Platelets are 25, low but holding relatively flat over the past several days.

Liver and kidney numbers are reassuring. ALT, AST, and bilirubin are all stable and well within normal range — her liver is handling this well. Creatinine is 0.74, consistent with where it's been all week, indicating her kidneys are steady. One number worth watching: alkaline phosphatase has been climbing gradually, from 62 on May 6 to 110 today. The team is aware; it's not at a level requiring alarm, but it's a trend they'll be tracking.

Mom received a unit of red blood cells on May 11 — the Hgb jump from 7.9 to 9.1 between yesterday and today is consistent with that transfusion taking effect. Platelets at 25 remain below the threshold where a platelet transfusion is typically considered; the team will be watching that number closely. This kind of transfusion support during induction is completely expected — it's how the team keeps her stable while her marrow works to recover.

How Mom's Likely Feeling Today 💛

🔋 Energy. Hgb 9.1 after yesterday's transfusion — likely mild fatigue, probably less winded than yesterday.

🛡️ Infection. ANC 0.2 — severely neutropenic; she likely feels normal, but the team is watching every degree of temperature.

🔥 Inflammation. LDH nudged up to 175 this week — some low-level inflammatory activity may still be present.

🤢 Stomach. Day 23, past the AZA window — her stomach is probably settling compared to mid-cycle.

Net read: Transfusion helped, ANC dangerously low but expected, marrow not yet recovering.

What changed today
Biggest day-over-day shifts — 2026-05-11 → 2026-05-12
ANC (neutrophils): 0.1 → 0.2 (+0.1 K/uL)
Neutrophils up — better infection defense today.
White Blood Cells: 2.5 → 0.9 (−1.6 K/uL)
Crossed into a alert zone — was watch. Worth flagging.
Hemoglobin: 7.9 → 9.1 (+1.2 g/dL)
Improved out of the watch zone into normal. Good direction.
1The Journey
Treatment timeline and what's coming up
This is the tentative plan right now. Nothing is locked in. The team will adjust based on how Mom responds, how her body handles each drug, and whether transplant becomes a real option. She could do fewer cycles, or more. Dates can shift. Treatment can continue up to 2 years total. Think of this as the current roadmap, not a fixed schedule.
The journey · First 4 cycles shown · Apr 20 → Aug 16 (may continue)
← swipe to see the full timeline →
C1
C2
C3
C4
Apr 20
May 24
Jun 21
Jul 19
Aug 16
Today
Nadunolimab infusion
Azacitidine week
Watch week (nadir)
Note: The trial can run up to 2 years. This chart shows the first 4 cycles as the initial window — Mom may continue past Aug 16 depending on her response and when a transplant is ready.
What's coming up
In 12 days
End of Cycle 1 · bone marrow biopsy
Sunday · May 24
In 13 days
Nadunolimab infusion
Monday · May 25
In 13 days
Azacitidine week begins
Monday · May 25
2The Numbers
Daily labs, transfusions, and the full data

Transfusions

7 detected — confirmed entries come from the manual log; inferred entries are deduced from lab jumps.
🩸 Transfusion log (7)
2026-04-02PRBC (1 unit)Pre-MDA transfusion at Aspirus. Hgb 8.0 → post-transfusion dilutional labs at MDA admit.(confirmed)
2026-04-06PRBC (red cells)Hgb +2.9, RDW -0.8 (revealed 2026-04-07 AM draw)(inferred from labs)
2026-04-11PRBC (red cells)Hgb +1.0, RDW +1.9 (revealed 2026-04-12 AM draw)(inferred from labs)
2026-04-22PRBC (red cells)Hgb +1.2, RDW +0.4 (revealed 2026-04-23 AM draw)(inferred from labs)
2026-04-24PRBC (red cells)Hgb +1.4, RDW -1.6 (revealed 2026-04-25 AM draw)(inferred from labs)
2026-05-01PRBC (red cells)Hgb +1.4, RDW -0.8 (revealed 2026-05-02 AM draw)(inferred from labs)
2026-05-11PRBC (red cells)Hgb +1.2, RDW -0.3 (revealed 2026-05-12 AM draw)(inferred from labs)

Blood Work

Daily labs from MD Anderson, ordered by day-to-day importance.
Green · on trackYellow · watchingRed · needs attention
Ordered by importance. The top row is what matters most day-to-day: ANC (infection risk), Hemoglobin (oxygen/energy), Platelets (bleeding risk), Blast % (disease activity), and RDW (marrow health).
= transfusion day (same as the 🩸 in the Full Data table)
Blood Counts — the daily headline numbers
1
ANC (neutrophils)
0.2K/uL▲ +0.12
Target ≥1.95 · ≤7.25 (MDA ref) · ↑ higher is better
The specific cells that fight bacteria. Under 1.0 + any fever = call the nurse right away.
2
Hemoglobin
9.1g/dL▲ +1.2
Target ≥12.2 · ≤15.3 (MDA ref) · ↑ higher is better
Carries oxygen through the body. Low = tired, short of breath. Transfusion likely under 8.
3
Platelets
25K/uL▲ +1
Target ≥160.0 · ≤397.0 (MDA ref) · ↑ higher is better
Tiny cells that stop bleeding. Low = bruising, bleeding. Transfusion likely under 20.
4
Peripheral blasts
1%
Target ≤0.0 (MDA ref) · ↓ lower is better
Immature cancer cells in the bloodstream. Goal is 0%. Lower = better.
5
RDW
17.2%▼ -0.3
Target ≥11.6 · ≤15.5 (MDA ref) · ↓ lower is better
How uneven the red blood cells are in size. Rising means her marrow is working harder.
6
White Blood Cells
0.9K/uL▼ -1.6
Target ≥4.1 · ≤10.5 (MDA ref) · ↑ higher is better
Total immune cells. Low = more vulnerable. Very high could mean infection or disease activity.
Chemistry — liver, kidneys, nutrition
7
ALT
17U/L▲ +1
Target ≤33.0 (MDA ref) · ↓ lower is better
Liver enzyme. Leaks out when liver cells are a little irritated. One she's watching.
8
AST
15U/L▲ +1
Target ≤32.0 (MDA ref) · ↓ lower is better
Another liver enzyme, pairs with ALT. Rising together means the liver wants a rest.
9
LDH
175U/L▲ +22
Target ≥135.0 · ≤214.0 (MDA ref) · ↓ lower is better
Leaks out when cells die fast. Falling means treatment is working. Rising = more turnover.
10
Creatinine
0.74mg/dL▼ -0.03
Target ≥0.51 · ≤0.95 (MDA ref) · ↓ lower is better
Best kidney function marker. Stable = kidneys happy. Chemo doses depend on this.
11
BUN
19mg/dL▼ -3
Target ≥6.0 · ≤23.0 (MDA ref) · ↓ lower is better
Kidney waste product. Rising can mean she needs more fluids or the kidneys are working hard.
12
Bilirubin
0.3mg/dL
Target ≥0.0 · ≤1.2 (MDA ref) · ↓ lower is better
Liver waste product. High can cause yellowing — hers is totally fine.
13
Alk Phos
110U/L▲ +20
Target ≥35.0 · ≤104.0 (MDA ref) · ↓ lower is better
Another liver/bile marker. Stable = plumbing's working.
14
Albumin
3.6g/dL▲ +0.3
Target ≥3.5 · ≤5.2 (MDA ref) · ↑ higher is better
Main blood protein. Low = could use more nutrition. Hers is a bit low.
Electrolytes — the balance panel
15
Potassium
4.4mmol/L▼ -0.3
Target ≥3.4 · ≤4.5 (MDA ref) · stay in range
Electrolyte. Right balance keeps the heart happy. Team watches this closely.
16
Uric acid
3.1mg/dL▼ -0.1
Target ≥2.4 · ≤5.7 (MDA ref) · stay in range
Waste from cells that are dying off. Allopurinol keeps it controlled.
17
Calcium
8.6mg/dL▼ -0.2
Target ≥8.2 · ≤10.2 (MDA ref) · stay in range
Electrolyte for bones, muscles, heart.
18
Phosphorus
2.8mg/dL▼ -1
Target ≥2.5 · ≤4.5 (MDA ref) · stay in range
Electrolyte the team watches when cancer cells are dying off.
19
Magnesium
1.9mg/dL
Target ≥1.6 · ≤2.6 (MDA ref) · stay in range
Electrolyte for muscles, nerves, heart. Easy to top up if low.

Full Data

Every value, every day. Colored cells flag out-of-range. 🩸 marks transfusion days.
Full Data
← swipe to see all dates →
Metric04-0104-0704-0804-0904-1004-11 🩸04-1204-1304-1404-1504-1604-1704-1804-1904-2004-2104-22 🩸04-2304-24 🩸04-2504-2604-2704-2804-2904-3005-01 🩸05-0205-0305-0405-0505-0605-0705-0805-0905-1005-11 🩸05-12
ANC (neutrophils)4.463.872.193.574.264.353.531.932.342.191.311.071.021.30.82.940.482.061.531.141.21.090.810.680.210.380.230.130.140.190.190.280.220.060.020.080.2
Hemoglobin810.99.498.37.78.78.88.98.48.58.68.38.58.18.37.897.89.29.28.7998.47.89.29.49.39.59.29.68.98.58.37.99.1
Platelets63565250495155575757646662605849524741394041434444383637353631322825242425
Peripheral blasts4451266411121013141075235332311
RDW21.220.420.320.520.119.721.620.820.520.220.120.120.220.420.520.820.721.120.518.918.918.418.518.618.818.918.118.11817.917.717.817.617.717.817.517.2
White Blood Cells6.757.97.38.38.26.97.59.298.17.77.16.85.45.74.24.47.15.95.74.34.22.63.432.42.53.33.53.13.23.53.132.32.50.9
ALT12272725244159615750444034384149453524201717181815162323222017161517171617
AST1217171816313834282223222022233024169121313111310111616141112121315161415
LDH196206193174152157178179154159178178158177181230216167148160164130150135134125126133140141144155146148158153175
Creatinine0.810.960.90.910.80.820.720.790.720.720.780.890.830.881.060.950.840.720.640.720.680.610.710.860.770.740.940.870.890.860.820.760.750.910.740.770.74
BUN242620202629282730312932273231292419191718242518192321232222212323202219
Bilirubin0.60.40.70.40.30.30.30.30.30.30.30.30.30.30.30.30.60.40.30.40.30.30.40.50.30.40.60.40.30.50.60.30.30.30.30.3
Alk Phos8876757469676673676772717676807370657167626661585457555760627174748690110
Albumin3.63.332.92.82.72.82.82.82.82.93.13.23.23.23.23.22.92.92.92.932.932.92.93.13.23.33.43.63.53.33.43.33.6
Potassium4.64.74.14.54.44.44.54.44.444.23.944.24.73.743.93.74.34.14.13.53.83.943.84.344.44.44.44.54.34.74.4
Uric acid32.62.32.122.12.22.12.22.52.62.72.43.13.23.12.72.62.82.62.62.92.92.72.92.82.93.13.33.33.33.63.43.23.1
Calcium99.38.899.18.98.98.88.99.198.898.898.88.78.88.88.9998.68.89.39.199.19.29.19.18.98.88.6
Phosphorus4.13.73233.133.53.53.73.83.53.72.82.53.73.43.13.73.33.23.63.43.13.53.63.33.13.43.844.13.63.82.8
Magnesium2.32.12.22.22.12.32.22.42.22.12.1221.821.81.81.91.91.91.81.91.81.82.12.22.22.32.22.221.91.91.91.9
3The Plan
Each drug, the cycle structure, and watch weeks

The Regimen

What each drug does, why it's in her protocol, and when she takes it.
Study 2023-0621 · MD Anderson · Dr. Michael Andreeff
What she has: High-risk MDS (myelodysplastic syndrome) with TP53 mutation and 17p deletion. A bone-marrow condition that traces back to chemo she had for breast cancer in 1993. She's formally MDS (7% immature cells), treated carefully because of her TP53 gene.
The plan: Two medicines teaming up, cycle by cycle (1 cycle ≈ 1 month). Trial can run up to 2 years. Goal: quiet the disease down enough to move toward a stem cell transplant — which offers the chance to heal fully. Transplant timing depends on her response, not a fixed number of cycles.
Nadunolimabinvestigational antibody, IV
🎯 Smart missile
Targets the cells that drive the disease, while leaving healthy cells alone.
C1: Days 1, 8, 22. C2+: Days 1 and 15 (every 2 weeks).
Azacitidine (AZA)FDA-approved, IV or small injection
🔄 Reset button
Flips helpful genes back on so cells behave more normally.
C1: Days 8–14 (7 days). C2+: Days 1–7 of each cycle.
C1Apr 20–May 24C2May 25–Jun 21C3Jun 22–Jul 19C4Jul 20–Aug 16
She's Now In Cycle 1
The First Four Cycles
Cycle 1Apr 20 – May 24
Starting strong. Both medicines begin (Nadunolimab + Azacitidine).
Cycle 2May 25 – Jun 21
If counts recover and the team clears it, possible move to Rotary House. Nothing about this is locked in — depends entirely on her response and the team's call.
Cycle 3Jun 22 – Jul 19
Possible chance to come home for a stretch if she's ready. Tentative — depends on response.
Cycle 4Jul 20 – Aug 16
Team evaluates response — could lead to transplant or more cycles.
Beyond Cycle 4Aug 16 +
Trial can run up to 2 years. Treatment continues cycle by cycle as long as she's responding. Stem cell transplant happens whenever the team says she's ready and a donor match is confirmed — could be sooner, could be later.

Watch Weeks

Rough estimates of when Mom's blood counts might be at their lowest each cycle. These are educated guesses based on typical Azacitidine-induction timing. Her actual lowest week can shift earlier or later, can last longer, and might not always be the first cycle. The team watches her daily regardless, so think of these more as heads-up windows than hard predictions.
Magnifying glass over blood cells
May 04 – May 18Cycle 1 watch window — Rough estimate of when her blood counts could be at their lowest during this cycle. Actual timing varies a lot patient to patient.
Jun 08 – Jun 21Cycle 2 watch window — Another likely dip window. Nadirs can get deeper over time, or not. Team adjusts as they learn her pattern.
Jul 05 – Jul 19Cycle 3 watch window — Third estimated dip. By now the team has a better feel for her rhythm, and these windows may shift.
Aug 03 – Aug 16Cycle 4 watch window — Last dip before a possible transplant conversation, depending on how she's responding.
We ❤️ You Mom!