Mom — Treatment Dashboard
TODAY · TUESDAY
May 12, 2026
Cycle 1
Day 23 of 35 · Watch week
66% through Cycle 1 · 18% through the first 4 cycles (trial can run up to 2 years)
Medicine schedule
NadunolimabNext in 13 days (May 25)
AzacitidineWeek starts in 13 days (May 25)
What Mom's Labs Say Today
Today is Day 23 of Cycle 1 — Lana is past the active treatment window and now in the recovery stretch, where the marrow does the slow work of rebuilding. Her Hgb (hemoglobin) came in at 9.1 today, up from 7.9 yesterday — that jump almost certainly reflects a red cell transfusion she received on May 11 (more on that below). Her ANC (neutrophils) is 0.2, which is severely low, and her platelet count is 25 — both very much in the zone we'd expect at this point in induction. Her white count also dropped sharply today to 0.9, which the team will be watching closely.
Her liver numbers — ALT 17, AST 15, bilirubin 0.3 — are calm and have been steady all week. Kidney function looks good too; creatinine is 0.74 and has been stable. One number worth noting is alkaline phosphatase, which has been quietly climbing across the past week (62 on May 6, up to 110 today). Her team is aware; it hasn't crossed into concerning territory, but it's a trend Megan will see on the data card.
She received a unit of red blood cells on May 11 — her hemoglobin had drifted down to 7.9 before the transfusion, and today's 9.1 reflects that support landing. Transfusions at this stage of induction are completely routine and expected; this is the marrow doing very little on its own right now, which is exactly what aggressive induction looks like. Platelets remain low at 25, and the team will be watching whether a platelet transfusion becomes needed.
How Mom's Likely Feeling Today 💛
🔋 Energy. Hgb 9.1 after yesterday's transfusion — probably a bit less winded than the past few days.
🛡️ Infection. ANC 0.2 — severely neutropenic; the team is watching her very closely right now.
📈 Inflammation. LDH has edged up to 175 this week — any bone aches may still be present.
🤢 Stomach. Day 23, past the AZA window — her stomach is probably starting to settle.
Net read: transfusion helping energy; infection risk is the main focus now.
What changed today
Biggest day-over-day shifts — 2026-05-11 → 2026-05-12
▲
ANC (neutrophils): 0.1 → 0.2 (+0.1 K/uL)
Neutrophils up — better infection defense today.
▼
White Blood Cells: 2.5 → 0.9 (−1.6 K/uL)
Crossed into a alert zone — was watch. Worth flagging.
▲
Hemoglobin: 7.9 → 9.1 (+1.2 g/dL)
Improved out of the watch zone into normal. Good direction.
This is the tentative plan right now. Nothing is locked in. The team will adjust based on how Mom responds, how her body handles each drug, and whether transplant becomes a real option. She could do fewer cycles, or more. Dates can shift. Treatment can continue up to 2 years total. Think of this as the current roadmap, not a fixed schedule.
The journey · First 4 cycles shown · Apr 20 → Aug 16 (may continue)
← swipe to see the full timeline →
C1
C2
C3
C4
Apr 20
May 24
Jun 21
Jul 19
Aug 16
Today
Nadunolimab infusion
Azacitidine week
Watch week (nadir)
Note: The trial can run up to 2 years. This chart shows the first 4 cycles as the initial window — Mom may continue past Aug 16 depending on her response and when a transplant is ready.
Transfusions
7 detected — confirmed entries come from the manual log; inferred entries are deduced from lab jumps.
🩸 Transfusion log (7)
2026-04-02PRBC (1 unit)Pre-MDA transfusion at Aspirus. Hgb 8.0 → post-transfusion dilutional labs at MDA admit.(confirmed)
2026-04-06PRBC (red cells)Hgb +2.9, RDW -0.8 (revealed 2026-04-07 AM draw)(inferred from labs)
2026-04-11PRBC (red cells)Hgb +1.0, RDW +1.9 (revealed 2026-04-12 AM draw)(inferred from labs)
2026-04-22PRBC (red cells)Hgb +1.2, RDW +0.4 (revealed 2026-04-23 AM draw)(inferred from labs)
2026-04-24PRBC (red cells)Hgb +1.4, RDW -1.6 (revealed 2026-04-25 AM draw)(inferred from labs)
2026-05-01PRBC (red cells)Hgb +1.4, RDW -0.8 (revealed 2026-05-02 AM draw)(inferred from labs)
2026-05-11PRBC (red cells)Hgb +1.2, RDW -0.3 (revealed 2026-05-12 AM draw)(inferred from labs)
Blood Work
Daily labs from MD Anderson, ordered by day-to-day importance.
Green · on trackYellow · watchingRed · needs attention
Ordered by importance. The top row is what matters most day-to-day: ANC (infection risk), Hemoglobin (oxygen/energy), Platelets (bleeding risk), Blast % (disease activity), and RDW (marrow health).
= transfusion day (same as the 🩸 in the Full Data table)
Blood Counts — the daily headline numbers
1
ANC (neutrophils)
0.2K/uL▲ +0.12
Target ≥1.95 · ≤7.25 (MDA ref) · ↑ higher is better
The specific cells that fight bacteria. Under 1.0 + any fever = call the nurse right away.
2
Hemoglobin
9.1g/dL▲ +1.2
Target ≥12.2 · ≤15.3 (MDA ref) · ↑ higher is better
Carries oxygen through the body. Low = tired, short of breath. Transfusion likely under 8.
3
Platelets
25K/uL▲ +1
Target ≥160.0 · ≤397.0 (MDA ref) · ↑ higher is better
Tiny cells that stop bleeding. Low = bruising, bleeding. Transfusion likely under 20.
4
Peripheral blasts
1%→
Target ≤0.0 (MDA ref) · ↓ lower is better
Immature cancer cells in the bloodstream. Goal is 0%. Lower = better.
5
RDW
17.2%▼ -0.3
Target ≥11.6 · ≤15.5 (MDA ref) · ↓ lower is better
How uneven the red blood cells are in size. Rising means her marrow is working harder.
6
White Blood Cells
0.9K/uL▼ -1.6
Target ≥4.1 · ≤10.5 (MDA ref) · ↑ higher is better
Total immune cells. Low = more vulnerable. Very high could mean infection or disease activity.
Chemistry — liver, kidneys, nutrition
7
ALT
17U/L▲ +1
Target ≤33.0 (MDA ref) · ↓ lower is better
Liver enzyme. Leaks out when liver cells are a little irritated. One she's watching.
8
AST
15U/L▲ +1
Target ≤32.0 (MDA ref) · ↓ lower is better
Another liver enzyme, pairs with ALT. Rising together means the liver wants a rest.
9
LDH
175U/L▲ +22
Target ≥135.0 · ≤214.0 (MDA ref) · ↓ lower is better
Leaks out when cells die fast. Falling means treatment is working. Rising = more turnover.
10
Creatinine
0.74mg/dL▼ -0.03
Target ≥0.51 · ≤0.95 (MDA ref) · ↓ lower is better
Best kidney function marker. Stable = kidneys happy. Chemo doses depend on this.
11
BUN
19mg/dL▼ -3
Target ≥6.0 · ≤23.0 (MDA ref) · ↓ lower is better
Kidney waste product. Rising can mean she needs more fluids or the kidneys are working hard.
12
Bilirubin
0.3mg/dL→
Target ≥0.0 · ≤1.2 (MDA ref) · ↓ lower is better
Liver waste product. High can cause yellowing — hers is totally fine.
13
Alk Phos
110U/L▲ +20
Target ≥35.0 · ≤104.0 (MDA ref) · ↓ lower is better
Another liver/bile marker. Stable = plumbing's working.
14
Albumin
3.6g/dL▲ +0.3
Target ≥3.5 · ≤5.2 (MDA ref) · ↑ higher is better
Main blood protein. Low = could use more nutrition. Hers is a bit low.
Electrolytes — the balance panel
15
Potassium
4.4mmol/L▼ -0.3
Target ≥3.4 · ≤4.5 (MDA ref) · stay in range
Electrolyte. Right balance keeps the heart happy. Team watches this closely.
16
Uric acid
3.1mg/dL▼ -0.1
Target ≥2.4 · ≤5.7 (MDA ref) · stay in range
Waste from cells that are dying off. Allopurinol keeps it controlled.
17
Calcium
8.6mg/dL▼ -0.2
Target ≥8.2 · ≤10.2 (MDA ref) · stay in range
Electrolyte for bones, muscles, heart.
18
Phosphorus
2.8mg/dL▼ -1
Target ≥2.5 · ≤4.5 (MDA ref) · stay in range
Electrolyte the team watches when cancer cells are dying off.
19
Magnesium
1.9mg/dL→
Target ≥1.6 · ≤2.6 (MDA ref) · stay in range
Electrolyte for muscles, nerves, heart. Easy to top up if low.
Full Data
Every value, every day. Colored cells flag out-of-range. 🩸 marks transfusion days.
Full Data
← swipe to see all dates →
| Metric | 04-01 | 04-07 | 04-08 | 04-09 | 04-10 | 04-11 🩸 | 04-12 | 04-13 | 04-14 | 04-15 | 04-16 | 04-17 | 04-18 | 04-19 | 04-20 | 04-21 | 04-22 🩸 | 04-23 | 04-24 🩸 | 04-25 | 04-26 | 04-27 | 04-28 | 04-29 | 04-30 | 05-01 🩸 | 05-02 | 05-03 | 05-04 | 05-05 | 05-06 | 05-07 | 05-08 | 05-09 | 05-10 | 05-11 🩸 | 05-12 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ANC (neutrophils) | 4.46 | 3.87 | 2.19 | 3.57 | 4.26 | 4.35 | 3.53 | 1.93 | 2.34 | 2.19 | 1.31 | 1.07 | 1.02 | 1.3 | 0.8 | 2.94 | 0.48 | 2.06 | 1.53 | 1.14 | 1.2 | 1.09 | 0.81 | 0.68 | 0.21 | 0.38 | 0.23 | 0.13 | 0.14 | 0.19 | 0.19 | 0.28 | 0.22 | 0.06 | 0.02 | 0.08 | 0.2 |
| Hemoglobin | 8 | 10.9 | 9.4 | 9 | 8.3 | 7.7 | 8.7 | 8.8 | 8.9 | 8.4 | 8.5 | 8.6 | 8.3 | 8.5 | 8.1 | 8.3 | 7.8 | 9 | 7.8 | 9.2 | 9.2 | 8.7 | 9 | 9 | 8.4 | 7.8 | 9.2 | 9.4 | 9.3 | 9.5 | 9.2 | 9.6 | 8.9 | 8.5 | 8.3 | 7.9 | 9.1 |
| Platelets | 63 | 56 | 52 | 50 | 49 | 51 | 55 | 57 | 57 | 57 | 64 | 66 | 62 | 60 | 58 | 49 | 52 | 47 | 41 | 39 | 40 | 41 | 43 | 44 | 44 | 38 | 36 | 37 | 35 | 36 | 31 | 32 | 28 | 25 | 24 | 24 | 25 |
| Peripheral blasts | 4 | 4 | 5 | 12 | 6 | 6 | 4 | 11 | 12 | 10 | 13 | 14 | 10 | 7 | 5 | 2 | 3 | 5 | 3 | 3 | 2 | 3 | 1 | 1 | — | — | — | — | — | — | — | — | — | — | — | — | — |
| RDW | 21.2 | 20.4 | 20.3 | 20.5 | 20.1 | 19.7 | 21.6 | 20.8 | 20.5 | 20.2 | 20.1 | 20.1 | 20.2 | 20.4 | 20.5 | 20.8 | 20.7 | 21.1 | 20.5 | 18.9 | 18.9 | 18.4 | 18.5 | 18.6 | 18.8 | 18.9 | 18.1 | 18.1 | 18 | 17.9 | 17.7 | 17.8 | 17.6 | 17.7 | 17.8 | 17.5 | 17.2 |
| White Blood Cells | 6.75 | 7.9 | 7.3 | 8.3 | 8.2 | 6.9 | 7.5 | 9.2 | 9 | 8.1 | 7.7 | 7.1 | 6.8 | 5.4 | 5.7 | 4.2 | 4.4 | 7.1 | 5.9 | 5.7 | 4.3 | 4.2 | 2.6 | 3.4 | 3 | 2.4 | 2.5 | 3.3 | 3.5 | 3.1 | 3.2 | 3.5 | 3.1 | 3 | 2.3 | 2.5 | 0.9 |
| ALT | 12 | 27 | 27 | 25 | 24 | 41 | 59 | 61 | 57 | 50 | 44 | 40 | 34 | 38 | 41 | 49 | 45 | 35 | 24 | 20 | 17 | 17 | 18 | 18 | 15 | 16 | 23 | 23 | 22 | 20 | 17 | 16 | 15 | 17 | 17 | 16 | 17 |
| AST | 12 | 17 | 17 | 18 | 16 | 31 | 38 | 34 | 28 | 22 | 23 | 22 | 20 | 22 | 23 | 30 | 24 | 16 | 9 | 12 | 13 | 13 | 11 | 13 | 10 | 11 | 16 | 16 | 14 | 11 | 12 | 12 | 13 | 15 | 16 | 14 | 15 |
| LDH | 196 | 206 | 193 | 174 | 152 | 157 | 178 | 179 | 154 | 159 | 178 | 178 | 158 | 177 | 181 | 230 | 216 | 167 | 148 | 160 | 164 | 130 | 150 | 135 | 134 | 125 | 126 | 133 | 140 | 141 | 144 | 155 | 146 | 148 | 158 | 153 | 175 |
| Creatinine | 0.81 | 0.96 | 0.9 | 0.91 | 0.8 | 0.82 | 0.72 | 0.79 | 0.72 | 0.72 | 0.78 | 0.89 | 0.83 | 0.88 | 1.06 | 0.95 | 0.84 | 0.72 | 0.64 | 0.72 | 0.68 | 0.61 | 0.71 | 0.86 | 0.77 | 0.74 | 0.94 | 0.87 | 0.89 | 0.86 | 0.82 | 0.76 | 0.75 | 0.91 | 0.74 | 0.77 | 0.74 |
| BUN | — | 24 | 26 | 20 | 20 | 26 | 29 | 28 | 27 | 30 | 31 | 29 | 32 | 27 | 32 | 31 | 29 | 24 | 19 | 19 | 17 | 18 | 24 | 25 | 18 | 19 | 23 | 21 | 23 | 22 | 22 | 21 | 23 | 23 | 20 | 22 | 19 |
| Bilirubin | — | 0.6 | 0.4 | 0.7 | 0.4 | 0.3 | 0.3 | 0.3 | 0.3 | 0.3 | 0.3 | 0.3 | 0.3 | 0.3 | 0.3 | 0.3 | 0.3 | 0.6 | 0.4 | 0.3 | 0.4 | 0.3 | 0.3 | 0.4 | 0.5 | 0.3 | 0.4 | 0.6 | 0.4 | 0.3 | 0.5 | 0.6 | 0.3 | 0.3 | 0.3 | 0.3 | 0.3 |
| Alk Phos | — | 88 | 76 | 75 | 74 | 69 | 67 | 66 | 73 | 67 | 67 | 72 | 71 | 76 | 76 | 80 | 73 | 70 | 65 | 71 | 67 | 62 | 66 | 61 | 58 | 54 | 57 | 55 | 57 | 60 | 62 | 71 | 74 | 74 | 86 | 90 | 110 |
| Albumin | 3.6 | — | 3.3 | 3 | 2.9 | 2.8 | 2.7 | 2.8 | 2.8 | 2.8 | 2.8 | 2.9 | 3.1 | 3.2 | 3.2 | 3.2 | 3.2 | 3.2 | 2.9 | 2.9 | 2.9 | 2.9 | 3 | 2.9 | 3 | 2.9 | 2.9 | 3.1 | 3.2 | 3.3 | 3.4 | 3.6 | 3.5 | 3.3 | 3.4 | 3.3 | 3.6 |
| Potassium | — | 4.6 | 4.7 | 4.1 | 4.5 | 4.4 | 4.4 | 4.5 | 4.4 | 4.4 | 4 | 4.2 | 3.9 | 4 | 4.2 | 4.7 | 3.7 | 4 | 3.9 | 3.7 | 4.3 | 4.1 | 4.1 | 3.5 | 3.8 | 3.9 | 4 | 3.8 | 4.3 | 4 | 4.4 | 4.4 | 4.4 | 4.5 | 4.3 | 4.7 | 4.4 |
| Uric acid | — | — | 3 | 2.6 | 2.3 | 2.1 | 2 | 2.1 | 2.2 | 2.1 | 2.2 | 2.5 | 2.6 | 2.7 | 2.4 | 3.1 | 3.2 | 3.1 | 2.7 | 2.6 | 2.8 | 2.6 | 2.6 | 2.9 | 2.9 | 2.7 | 2.9 | 2.8 | 2.9 | 3.1 | 3.3 | 3.3 | 3.3 | 3.6 | 3.4 | 3.2 | 3.1 |
| Calcium | — | — | — | 9 | 9.3 | 8.8 | 9 | 9.1 | 8.9 | 8.9 | 8.8 | 8.9 | 9.1 | 9 | 8.8 | 9 | 8.8 | 9 | 8.8 | 8.7 | 8.8 | 8.8 | 8.9 | 9 | 9 | 8.6 | 8.8 | 9.3 | 9.1 | 9 | 9.1 | 9.2 | 9.1 | 9.1 | 8.9 | 8.8 | 8.6 |
| Phosphorus | — | — | 4.1 | 3.7 | 3 | 2 | 3 | 3.1 | 3 | 3.5 | 3.5 | 3.7 | 3.8 | 3.5 | 3.7 | 2.8 | 2.5 | 3.7 | 3.4 | 3.1 | 3.7 | 3.3 | 3.2 | 3.6 | 3.4 | 3.1 | 3.5 | 3.6 | 3.3 | 3.1 | 3.4 | 3.8 | 4 | 4.1 | 3.6 | 3.8 | 2.8 |
| Magnesium | — | — | 2.3 | 2.1 | 2.2 | 2.2 | 2.1 | 2.3 | 2.2 | 2.4 | 2.2 | 2.1 | 2.1 | 2 | 2 | 1.8 | 2 | 1.8 | 1.8 | 1.9 | 1.9 | 1.9 | 1.8 | 1.9 | 1.8 | 1.8 | 2.1 | 2.2 | 2.2 | 2.3 | 2.2 | 2.2 | 2 | 1.9 | 1.9 | 1.9 | 1.9 |
The Regimen
What each drug does, why it's in her protocol, and when she takes it.
What she has: High-risk MDS (myelodysplastic syndrome) with TP53 mutation and 17p deletion. A bone-marrow condition that traces back to chemo she had for breast cancer in 1993. She's formally MDS (7% immature cells), treated carefully because of her TP53 gene.
The plan: Two medicines teaming up, cycle by cycle (1 cycle ≈ 1 month). Trial can run up to 2 years. Goal: quiet the disease down enough to move toward a stem cell transplant — which offers the chance to heal fully. Transplant timing depends on her response, not a fixed number of cycles.
Nadunolimabinvestigational antibody, IV
Targets the cells that drive the disease, while leaving healthy cells alone.
C1: Days 1, 8, 22. C2+: Days 1 and 15 (every 2 weeks).
Azacitidine (AZA)FDA-approved, IV or small injection
Flips helpful genes back on so cells behave more normally.
C1: Days 8–14 (7 days). C2+: Days 1–7 of each cycle.
She's Now In Cycle 1
The First Four Cycles
Cycle 1Apr 20 – May 24
Starting strong. Both medicines begin (Nadunolimab + Azacitidine).
Cycle 2May 25 – Jun 21
If counts recover and the team clears it, possible move to Rotary House. Nothing about this is locked in — depends entirely on her response and the team's call.
Cycle 3Jun 22 – Jul 19
Possible chance to come home for a stretch if she's ready. Tentative — depends on response.
Cycle 4Jul 20 – Aug 16
Team evaluates response — could lead to transplant or more cycles.
Beyond Cycle 4Aug 16 +
Trial can run up to 2 years. Treatment continues cycle by cycle as long as she's responding. Stem cell transplant happens whenever the team says she's ready and a donor match is confirmed — could be sooner, could be later.
Watch Weeks
Rough estimates of when Mom's blood counts might be at their lowest each cycle. These are educated guesses based on typical Azacitidine-induction timing. Her actual lowest week can shift earlier or later, can last longer, and might not always be the first cycle. The team watches her daily regardless, so think of these more as heads-up windows than hard predictions.
May 04 – May 18Cycle 1 watch window — Rough estimate of when her blood counts could be at their lowest during this cycle. Actual timing varies a lot patient to patient.
Jun 08 – Jun 21Cycle 2 watch window — Another likely dip window. Nadirs can get deeper over time, or not. Team adjusts as they learn her pattern.
Jul 05 – Jul 19Cycle 3 watch window — Third estimated dip. By now the team has a better feel for her rhythm, and these windows may shift.
Aug 03 – Aug 16Cycle 4 watch window — Last dip before a possible transplant conversation, depending on how she's responding.
We ❤️ You Mom!