Mom — Treatment Dashboard

Lana Markey · Study 2023-0621 · Dr. Andreeff, MD Anderson

Latest labs: 2026-05-13 · Built 2026-05-13 09:41:26
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TODAY · WEDNESDAY

May 13, 2026

Cycle 1

Day 24 of 35 · Watch week

69% through Cycle 1 · 19% through the first 4 cycles (trial can run up to 2 years)

Medicine schedule

💉NadunolimabNext in 12 days (May 25)

💉AzacitidineWeek starts in 12 days (May 25)

What Mom's Labs Say Today

Auto-generated from Mom's MyChart labs with AI assistance. This is an informational summary, not medical advice or a clinical assessment — any questions or concerns should go to her care team at MD Anderson. Every number cites a date; causal claims are hedged.

Mom is on Cycle 1 Day 24 of 35 (2026-05-13). Her peripheral blast count was 1.0% on 2026-04-29, down from a peak of 5.0% on 2026-04-23. The first Nadunolimab infusion was given Apr 20. The timing of the decline is consistent with that drug contributing, but blast counts were already trending down before the infusion, so we can't confidently attribute the drop to any single factor. Azacitidine doesn't start until Day 8 of the cycle.

Hemoglobin is 8.2 g/dL on 2026-05-13. Platelets are 23.0 K/uL — at/near the 20 transfusion threshold. ANC (neutrophils) is 0.09 K/uL on 2026-05-13 — this is severe neutropenia. Any fever above 100.4°F requires an immediate call to MDA. Day 3 of induction is early for chemo-driven nadir (typically Day 10-14). Today's low ANC (neutrophils) most likely reflects her underlying MDS marrow failure more than a direct effect of Nadunolimab.

ALT is 16.0 U/L on 2026-05-13 — within the reference range. Kidney function looks stable (creatinine 0.82 mg/dL on 2026-05-13).

Transfusions in the last 7 days: 2026-05-11 PRBC (red cells) (inferred). Note: MDA typically draws morning labs just after midnight, so a transfusion given overnight will not show up until the next day's draw.

How Mom's Likely Feeling Today 💛

🌬️ Energy & breath. Hemoglobin 8.2 g/dL on 2026-05-13 is mildly low — she's probably tired, and likely a bit easily winded climbing stairs or talking for long stretches.

💧 Hydration. Creatinine, BUN, and sodium are all trending up over the last few days while potassium has dipped — a textbook signature of fluid running a little behind. She's likely thirsty, possibly with a dry mouth, and may feel lightheaded standing up.

🛡️ Infection vulnerability. ANC (neutrophils) 0.09 on 2026-05-13 is severe neutropenia. She likely feels normal on this front — neutropenia itself is silent — but she's vulnerable. The team is on this; any fever ≥ 100.4°F triggers immediate workup.

Net read: today's numbers describe a body being asked to do a hard thing and holding up. Tired, watched closely, no surprises.

What changed today

Biggest day-over-day shifts — 2026-05-12 → 2026-05-13

▲

White Blood Cells: 0.9 → 3.1 (+2.2 K/uL)

Improved out of the alert zone into watch. Good direction.

▼

ANC (neutrophils): 0.2 → 0.1 (−0.1 K/uL)

Neutrophils trending down — expected during induction.

▲

BUN: 19 → 25 (+6 mg/dL)

Crossed into a watch zone — was normal. Worth flagging.

This is the tentative plan right now. Nothing is locked in. The team will adjust based on how Mom responds, how her body handles each drug, and whether transplant becomes a real option. She could do fewer cycles, or more. Dates can shift. Treatment can continue up to 2 years total. Think of this as the current roadmap, not a fixed schedule.

The journey · First 4 cycles shown · Apr 20 → Aug 16 (may continue)

← swipe to see the full timeline →

Apr 20

May 24

Jun 21

Jul 19

Aug 16

Today

Nadunolimab infusion

Azacitidine week

Watch week (nadir)

Note: The trial can run up to 2 years. This chart shows the first 4 cycles as the initial window — Mom may continue past Aug 16 depending on her response and when a transplant is ready.

What's coming up

In 11 days

End of Cycle 1 · bone marrow biopsy

Sunday · May 24

In 12 days

Nadunolimab infusion

Monday · May 25

In 12 days

Azacitidine week begins

Monday · May 25

Transfusions

7 detected — confirmed entries come from the manual log; inferred entries are deduced from lab jumps.

🩸 Transfusion log (7)

2026-04-02PRBC (1 unit)Pre-MDA transfusion at Aspirus. Hgb 8.0 → post-transfusion dilutional labs at MDA admit.(confirmed)

2026-04-06PRBC (red cells)Hgb +2.9, RDW -0.8 (revealed 2026-04-07 AM draw)(inferred from labs)

2026-04-11PRBC (red cells)Hgb +1.0, RDW +1.9 (revealed 2026-04-12 AM draw)(inferred from labs)

2026-04-22PRBC (red cells)Hgb +1.2, RDW +0.4 (revealed 2026-04-23 AM draw)(inferred from labs)

2026-04-24PRBC (red cells)Hgb +1.4, RDW -1.6 (revealed 2026-04-25 AM draw)(inferred from labs)

2026-05-01PRBC (red cells)Hgb +1.4, RDW -0.8 (revealed 2026-05-02 AM draw)(inferred from labs)

2026-05-11PRBC (red cells)Hgb +1.2, RDW -0.3 (revealed 2026-05-12 AM draw)(inferred from labs)

Blood Work

Daily labs from MD Anderson, ordered by day-to-day importance.

Green · on trackYellow · watchingRed · needs attention

Ordered by importance. The top row is what matters most day-to-day: ANC (infection risk), Hemoglobin (oxygen/energy), Platelets (bleeding risk), Blast % (disease activity), and RDW (marrow health).

= transfusion day (same as the 🩸 in the Full Data table)

Blood Counts — the daily headline numbers

ANC (neutrophils)

0.09K/uL▼ -0.11

Target ≥1.95 · ≤7.25 (MDA ref) · ↑ higher is better

The specific cells that fight bacteria. Under 1.0 + any fever = call the nurse right away.

Hemoglobin

8.2g/dL▼ -0.9

Target ≥12.2 · ≤15.3 (MDA ref) · ↑ higher is better

Carries oxygen through the body. Low = tired, short of breath. Transfusion likely under 8.

Platelets

23K/uL▼ -2

Target ≥160.0 · ≤397.0 (MDA ref) · ↑ higher is better

Tiny cells that stop bleeding. Low = bruising, bleeding. Transfusion likely under 20.

Peripheral blasts

1%→

Target ≤0.0 (MDA ref) · ↓ lower is better

Immature cancer cells in the bloodstream. Goal is 0%. Lower = better.

RDW

17.2%→

Target ≥11.6 · ≤15.5 (MDA ref) · ↓ lower is better

How uneven the red blood cells are in size. Rising means her marrow is working harder.

White Blood Cells

3.1K/uL▲ +2.2

Target ≥4.1 · ≤10.5 (MDA ref) · ↑ higher is better

Total immune cells. Low = more vulnerable. Very high could mean infection or disease activity.

Chemistry — liver, kidneys, nutrition

ALT

16U/L▼ -1

Target ≤33.0 (MDA ref) · ↓ lower is better

Liver enzyme. Leaks out when liver cells are a little irritated. One she's watching.

AST

14U/L▼ -1

Target ≤32.0 (MDA ref) · ↓ lower is better

Another liver enzyme, pairs with ALT. Rising together means the liver wants a rest.

LDH

169U/L▼ -6

Target ≥135.0 · ≤214.0 (MDA ref) · ↓ lower is better

Leaks out when cells die fast. Falling means treatment is working. Rising = more turnover.

Creatinine

0.82mg/dL▲ +0.08

Target ≥0.51 · ≤0.95 (MDA ref) · ↓ lower is better

Best kidney function marker. Stable = kidneys happy. Chemo doses depend on this.

BUN

25mg/dL▲ +6

Target ≥6.0 · ≤23.0 (MDA ref) · ↓ lower is better

Kidney waste product. Rising can mean she needs more fluids or the kidneys are working hard.

Bilirubin

0.3mg/dL→

Target ≥0.0 · ≤1.2 (MDA ref) · ↓ lower is better

Liver waste product. High can cause yellowing — hers is totally fine.

Alk Phos

94U/L▼ -16

Target ≥35.0 · ≤104.0 (MDA ref) · ↓ lower is better

Another liver/bile marker. Stable = plumbing's working.

Albumin

3.2g/dL▼ -0.4

Target ≥3.5 · ≤5.2 (MDA ref) · ↑ higher is better

Main blood protein. Low = could use more nutrition. Hers is a bit low.

Electrolytes — the balance panel

Potassium

4.4mmol/L→

Target ≥3.4 · ≤4.5 (MDA ref) · stay in range

Electrolyte. Right balance keeps the heart happy. Team watches this closely.

Uric acid

3.6mg/dL▲ +0.5

Target ≥2.4 · ≤5.7 (MDA ref) · stay in range

Waste from cells that are dying off. Allopurinol keeps it controlled.

Calcium

8.5mg/dL▼ -0.1

Target ≥8.2 · ≤10.2 (MDA ref) · stay in range

Electrolyte for bones, muscles, heart.

Phosphorus

4.2mg/dL▲ +1.4

Target ≥2.5 · ≤4.5 (MDA ref) · stay in range

Electrolyte the team watches when cancer cells are dying off.

Magnesium

2mg/dL▲ +0.1

Target ≥1.6 · ≤2.6 (MDA ref) · stay in range

Electrolyte for muscles, nerves, heart. Easy to top up if low.

Full Data

Every value, every day. Colored cells flag out-of-range. 🩸 marks transfusion days.

Full Data

← swipe to see all dates →

Metric	04-01	04-07	04-08	04-09	04-10	04-11 🩸	04-12	04-13	04-14	04-15	04-16	04-17	04-18	04-19	04-20	04-21	04-22 🩸	04-23	04-24 🩸	04-25	04-26	04-27	04-28	04-29	04-30	05-01 🩸	05-02	05-03	05-04	05-05	05-06	05-07	05-08	05-09	05-10	05-11 🩸	05-12	05-13
ANC (neutrophils)	4.46	3.87	2.19	3.57	4.26	4.35	3.53	1.93	2.34	2.19	1.31	1.07	1.02	1.3	0.8	2.94	0.48	2.06	1.53	1.14	1.2	1.09	0.81	0.68	0.21	0.38	0.23	0.13	0.14	0.19	0.19	0.28	0.22	0.06	0.02	0.08	0.2	0.09
Hemoglobin	8	10.9	9.4	9	8.3	7.7	8.7	8.8	8.9	8.4	8.5	8.6	8.3	8.5	8.1	8.3	7.8	9	7.8	9.2	9.2	8.7	9	9	8.4	7.8	9.2	9.4	9.3	9.5	9.2	9.6	8.9	8.5	8.3	7.9	9.1	8.2
Platelets	63	56	52	50	49	51	55	57	57	57	64	66	62	60	58	49	52	47	41	39	40	41	43	44	44	38	36	37	35	36	31	32	28	25	24	24	25	23
Peripheral blasts	4	4	5	12	6	6	4	11	12	10	13	14	10	7	5	2	3	5	3	3	2	3	1	1	—	—	—	—	—	—	—	—	—	—	—	—	—	—
RDW	21.2	20.4	20.3	20.5	20.1	19.7	21.6	20.8	20.5	20.2	20.1	20.1	20.2	20.4	20.5	20.8	20.7	21.1	20.5	18.9	18.9	18.4	18.5	18.6	18.8	18.9	18.1	18.1	18	17.9	17.7	17.8	17.6	17.7	17.8	17.5	17.2	17.2
White Blood Cells	6.75	7.9	7.3	8.3	8.2	6.9	7.5	9.2	9	8.1	7.7	7.1	6.8	5.4	5.7	4.2	4.4	7.1	5.9	5.7	4.3	4.2	2.6	3.4	3	2.4	2.5	3.3	3.5	3.1	3.2	3.5	3.1	3	2.3	2.5	0.9	3.1
ALT	12	27	27	25	24	41	59	61	57	50	44	40	34	38	41	49	45	35	24	20	17	17	18	18	15	16	23	23	22	20	17	16	15	17	17	16	17	16
AST	12	17	17	18	16	31	38	34	28	22	23	22	20	22	23	30	24	16	9	12	13	13	11	13	10	11	16	16	14	11	12	12	13	15	16	14	15	14
LDH	196	206	193	174	152	157	178	179	154	159	178	178	158	177	181	230	216	167	148	160	164	130	150	135	134	125	126	133	140	141	144	155	146	148	158	153	175	169
Creatinine	0.81	0.96	0.9	0.91	0.8	0.82	0.72	0.79	0.72	0.72	0.78	0.89	0.83	0.88	1.06	0.95	0.84	0.72	0.64	0.72	0.68	0.61	0.71	0.86	0.77	0.74	0.94	0.87	0.89	0.86	0.82	0.76	0.75	0.91	0.74	0.77	0.74	0.82
BUN	—	24	26	20	20	26	29	28	27	30	31	29	32	27	32	31	29	24	19	19	17	18	24	25	18	19	23	21	23	22	22	21	23	23	20	22	19	25
Bilirubin	—	0.6	0.4	0.7	0.4	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.6	0.4	0.3	0.4	0.3	0.3	0.4	0.5	0.3	0.4	0.6	0.4	0.3	0.5	0.6	0.3	0.3	0.3	0.3	0.3	0.3
Alk Phos	—	88	76	75	74	69	67	66	73	67	67	72	71	76	76	80	73	70	65	71	67	62	66	61	58	54	57	55	57	60	62	71	74	74	86	90	110	94
Albumin	3.6	—	3.3	3	2.9	2.8	2.7	2.8	2.8	2.8	2.8	2.9	3.1	3.2	3.2	3.2	3.2	3.2	2.9	2.9	2.9	2.9	3	2.9	3	2.9	2.9	3.1	3.2	3.3	3.4	3.6	3.5	3.3	3.4	3.3	3.6	3.2
Potassium	—	4.6	4.7	4.1	4.5	4.4	4.4	4.5	4.4	4.4	4	4.2	3.9	4	4.2	4.7	3.7	4	3.9	3.7	4.3	4.1	4.1	3.5	3.8	3.9	4	3.8	4.3	4	4.4	4.4	4.4	4.5	4.3	4.7	4.4	4.4
Uric acid	—	—	3	2.6	2.3	2.1	2	2.1	2.2	2.1	2.2	2.5	2.6	2.7	2.4	3.1	3.2	3.1	2.7	2.6	2.8	2.6	2.6	2.9	2.9	2.7	2.9	2.8	2.9	3.1	3.3	3.3	3.3	3.6	3.4	3.2	3.1	3.6
Calcium	—	—	—	9	9.3	8.8	9	9.1	8.9	8.9	8.8	8.9	9.1	9	8.8	9	8.8	9	8.8	8.7	8.8	8.8	8.9	9	9	8.6	8.8	9.3	9.1	9	9.1	9.2	9.1	9.1	8.9	8.8	8.6	8.5
Phosphorus	—	—	4.1	3.7	3	2	3	3.1	3	3.5	3.5	3.7	3.8	3.5	3.7	2.8	2.5	3.7	3.4	3.1	3.7	3.3	3.2	3.6	3.4	3.1	3.5	3.6	3.3	3.1	3.4	3.8	4	4.1	3.6	3.8	2.8	4.2
Magnesium	—	—	2.3	2.1	2.2	2.2	2.1	2.3	2.2	2.4	2.2	2.1	2.1	2	2	1.8	2	1.8	1.8	1.9	1.9	1.9	1.8	1.9	1.8	1.8	2.1	2.2	2.2	2.3	2.2	2.2	2	1.9	1.9	1.9	1.9	2

The Regimen

What each drug does, why it's in her protocol, and when she takes it.

Study 2023-0621 · MD Anderson · Dr. Michael Andreeff

What she has: High-risk MDS (myelodysplastic syndrome) with TP53 mutation and 17p deletion. A bone-marrow condition that traces back to chemo she had for breast cancer in 1993. She's formally MDS (7% immature cells), treated carefully because of her TP53 gene.

The plan: Two medicines teaming up, cycle by cycle (1 cycle ≈ 1 month). Trial can run up to 2 years. Goal: quiet the disease down enough to move toward a stem cell transplant — which offers the chance to heal fully. Transplant timing depends on her response, not a fixed number of cycles.

Nadunolimabinvestigational antibody, IV

🎯 Smart missile

Targets the cells that drive the disease, while leaving healthy cells alone.

C1: Days 1, 8, 22. C2+: Days 1 and 15 (every 2 weeks).

Azacitidine (AZA)FDA-approved, IV or small injection

🔄 Reset button

Flips helpful genes back on so cells behave more normally.

C1: Days 8–14 (7 days). C2+: Days 1–7 of each cycle.

She's Now In Cycle 1

The First Four Cycles

Cycle 1Apr 20 – May 24

Starting strong. Both medicines begin (Nadunolimab + Azacitidine).

Cycle 2May 25 – Jun 21

If counts recover and the team clears it, possible move to Rotary House. Nothing about this is locked in — depends entirely on her response and the team's call.

Cycle 3Jun 22 – Jul 19

Possible chance to come home for a stretch if she's ready. Tentative — depends on response.

Cycle 4Jul 20 – Aug 16

Team evaluates response — could lead to transplant or more cycles.

Beyond Cycle 4Aug 16 +

Trial can run up to 2 years. Treatment continues cycle by cycle as long as she's responding. Stem cell transplant happens whenever the team says she's ready and a donor match is confirmed — could be sooner, could be later.

Watch Weeks

Rough estimates of when Mom's blood counts might be at their lowest each cycle. These are educated guesses based on typical Azacitidine-induction timing. Her actual lowest week can shift earlier or later, can last longer, and might not always be the first cycle. The team watches her daily regardless, so think of these more as heads-up windows than hard predictions.

May 04 – May 18Cycle 1 watch window — Rough estimate of when her blood counts could be at their lowest during this cycle. Actual timing varies a lot patient to patient.

Jun 08 – Jun 21Cycle 2 watch window — Another likely dip window. Nadirs can get deeper over time, or not. Team adjusts as they learn her pattern.

Jul 05 – Jul 19Cycle 3 watch window — Third estimated dip. By now the team has a better feel for her rhythm, and these windows may shift.

Aug 03 – Aug 16Cycle 4 watch window — Last dip before a possible transplant conversation, depending on how she's responding.

We ❤️ You Mom!

How this works: Daily lab pulls land in 02_Labs/daily_pulls/ as JSON. Transfusions are auto-detected when hemoglobin jumps ≥1.0 with an RDW spike (red cells) or platelets jump ≥20. Confirmed transfusions can be logged manually in 02_Labs/transfusions.json. Re-run python3 scripts/build_dashboard.py anytime to refresh.